Nitromethane-Condensation Reaction with 5-Aldehydes of Pentodialdofuranosides

Reaction of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol

Reactions of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol in a 1:1:1 molar ratio, afforded 5-(5-aryl-4-benzoyl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-1,3,4-thiadizole-2-thiols (3a-c). The structure of the resulted products was confirmed by determination of the melting point and spectrophotometric techniques such as IR and 1H-NMR spectroscopy.

Four-Component Reaction between Ethyl Benzoylacetate, Hydroxylamine, Aldehydes and Malononitrile: Synthesis of Isoxazol-5(2H)-Ones

We present herein a new and efficient four-component synthesis of isoxazol-5(2H)-ones involving ring closing/Knoevenagel condensation/Michael addition sequential reactions.

Microwave Enhanced Knoevenagel Condensation of Barbituric Acid with Aromatic Aldehydes on Basic Alumina

Efficient Knoevenagel condensation of barbituric acid with different aromatic aldehydes on basic alumina was performed in a conventional microwave over in the absence of solvent.

Kinetic Studies of Condensation of Aromatic Aldehydes with Meldrum’s Acid

The condensation reaction of Meldrum’s acid with aromatic aldehydes in the presence of a catalyst has been investigated spectrophotometrically at 25Ð50 ∞C. The reaction follows overall second order kinetics, first order in each of the reactants. Electron-withdrawing groups accelerate and electron-releasing groups retard the rate of condensation. From the dependence of the rate constants on temp...

The Condensation of Aromatic Aldehydes with Glycine and Acetylglycine